Acquiring new knowledge on the occurrence and development of diseases represents an important step towards their timely detection and successful treatment. Biomedical research implements modern science and plays a key role in reducing the morbidity and mortality rate of serious diseases, as well as improving people’s health and the quality of their lives. The project supports a multidisciplinary approach to biomedical research in Slovakia and mutual cooperation among research institutions in the European research area, as well as the implementation of knowledge in practice.
“We live in a world of rapid development and constantly discover new facts about diseases, particularly their causes and behaviour. Getting a correct diagnosis is not sufficient any more. Every patient is unique. The development of a disease is different in each and every case. The treatment may require different methods and approaches. Therefore, we are increasingly aware of the need for personalized medicine and targeted treatment requiring close cooperation of physicians and properly equipped research institutions at hand. The technical support provided for the completion of such a research centre, combined with a proper working environment ensured by our solutions, will bring significant benefits to patients in future.”
MUDr. Pavol Janega, PhD., Project Coordinator
Purpose of the Project
Oncologic diseases are the project’s key priority because they represent a serious medical issue, as well as a social one. Even though we are already aware of many determining factors, the etiology of their occurrence and factors influencing their progression are often unknown. Malignant tumours are generally seen as genetic diseases. They are caused by the accumulation of changes on the genetic level as a result of mutations accumulated in cells. Due to these genetic changes, cell characteristics change and they start to multiply uncontrollably. The body is not able to regulate their growth, which gradually becomes autonomous and uncontrollable. As more and more changes accumulate, the tumour acquires an ability to spread and create metastases. Due to the changes in cell surface composition, the tumour becomes invisible to the immune system and remains unnoticed to its control activity. Regardless of the cause, a large number of various aberrations on the genetic level and changes to the protein composition occur in tumour cells. If these changes are correctly and effectively identified using suitable genetic and proteomic laboratory diagnostic methods, it is possible to detect neoplastic processes at an early stage, which leads to correct diagnostics, good prognosis and targeted treatment of oncological patients.
In cooperation with other partners, we managed to build a high-tech multidisciplinary research centre focused on research in biomedicine, timely diagnostics for serious diseases, and identifying new potential diagnostic, prognostic and therapeutic markers. The quality of the biomedical centre is comparable to renowned international organizations of research and development and has potential to significantly contribute to research in the area of both malignant and non-malignant diseases in future. The international consortium of research groups established within the project focuses on the preparation of follow-up research projects and their successful solutions.
Project start date: 26th October, 2015
Project finish date: 31st December, 2015
Total eligible project incurred costs: 5,076,098.17 €
Project Target: Ensure good-quality infrastructure for the implementation of advanced research and development in biomedicine.
Build a centre of excellent international biomedical research – BIOMEDIRES implementing the know-how of foreign research partners focused on the following research areas:
– cytology and histology,
– equipment for glass-coated wires production
Specific project target: To build a modern infrastructure for research and development in biomedicine.
Complete the infrastructure for top-level cancer research, with special emphasis on the implementation of scientific findings in practice (project finish date: 31st December, 2015).
The Biomedires project is carried out in modernized labs using the equipment listed below. The technology is freely accessible to all scientists and researchers who intend to carry out independent research in public interest.
The equipment cannot be used for economic purposes.
For independent biomedical research using the listed technology, please, contact us at firstname.lastname@example.org.
Activities scheduled between 2016 – 2020:
- Create an international consortium of renowned scientific groups from Germany (e.g. University of Heidelberg) and Slovakia (e.g. Comenius University in Bratislava) with extensive experience in the implementation of research and development in practice (deadline: September 2016).
- Definition of a detailed research and development plan and individual sub-plans for the period between 2016 and 2020 (deadline: September 2016).
- Implementation of research and development before 2020 – examples of topics to be covered:
- Research and development with a view to improving tumour diagnostics as well as tumour monitoring methods during treatment,
- Research and development with a view to identifying new biomarkers of diagnostic and therapeutic value,
- Implementation of innovative activities in research and development in modern magnetic materials and their application in medicine (secondarily in compliance with RIS3 to be potentially used in electrotechnology in the automotive and construction industries),
- Research and development focused on miniature sensors and actuators, if their dimensions allow them to be incorporated into various materials, parts of the human body, without changing their mechanical qualities or influencing mechanical or biological functions,
Research focused on new materials produced by the IT and electrotechnical industries and their utilization in medicine
Recipient: MEDIREX GROUP ACADEMY n. o. (NPO)
- “Construction of Infrastructure” start date: 26th October, 2015
- “Construction of Infrastructure” finish date: 31st December, 2015
- Trial operation of research infrastructure and preparation for research and development: from 1st January, 2016 to 31st August, 2016
- Networking with foreign and domestic partners in scheduled research activities: from 1st January, 2016 to 30th September, 2016
- Launch of research and development activities: 1st October, 2016